The Cat’s Unique Physiological Adaptations to Carnivory

In addition to genetic, behavioural and anatomic adaptations, house cats also show around 14 physiological adaptations as obligate carnivores. When compared with the physiology of their closest wild progenitors, it becomes clear that domestic cats have retained all of their carnivore mechanisms.

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"Domestic cats are generally considered to have descended from the Old World wildcats" – Carlos Driscoll, PhD

The previous two blog posts focused on the house cat’s fascinating heritage as strict or obligate carnivores. Firstly, Are House Cats Still Carnivores? answered this question in some depth.

Meet the Wild Ancestors of the House Cat looked at their genetic wildcat ancestry and explored their closest wild progenitors.

Where’s the Proof that House Cats are Strict Carnivores? looked at the house cat’s wide array of special adaptations – genetic, anatomic and behavioural – to an all meat diet.

This post looks particularly at the adaptations in the cat’s biology as the final tier of proof of their status as true carnivores.

The distinctive physiology of the cat

James G. Morris, molecular bio-scientist and professor of biology, refers to the distinct characteristics of domestic cats as idiosyncratic, evolutionary and dietary induced adaptations that stem from strict carnivory 1.

Modern domestic cats are quite remarkable. They have retained all of their hyper carnivorous mechanisms from their wild progenitors for food selection 2.

...without further ado, the 14 most salient adaptations:

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01 Cats have a uniquely high requirement for animal basedprotein. They are unable to downregulate liver enzymes when protein intake is insufficient. Inadequate protein in the diet causes serious malnutrition and muscle wasting.
02 Cats are unable to perform arginine synthesis and require preformed arginine from animal tissues.
03 Cats are unable to perform taurine synthesis and require preformed taurine from animal muscle tissues.
04 Cats are unable to convert carotenoids into vitamin A and require preformed, active vitamin A from animal organs.
05 Even after more than adequate sunlight exposure, cats are unable to perform endogenous vitamin D synthesis. They require preformed vitamin D from animal organs and tissues.
06 Cats are unable to synthesise niacin from tryptophan and require preformed niacin from animal tissues.
07 Cats are unable to convert linoleic acid into arachdonic acid and require preformed arachdonic acid from animal tissue and organs. 
08 Cats have the unique ability to catabolise and use amino acids from animal tissues as a source of energy.
09 Cats have unique and often limited enzymatic capabilities because they are designed to use the enzymes present in fresh, raw animal tissues. 
10 Cats require tyrosine from animal tissue for melanin synthesis to develop full, rich coat colour.
11 Cats have very limited use for carbohydrates in the diet and do not metabolise them well.
12 Cats have very limited capabilities to synthesise EPA and DHA (omega-3 fatty acids). Cats need to fill these requirements from animal tissue. 
13 Cats have very limited capabilities to metabolise plant matter.  Plant based nutrients are not absorbed well and have poor bioavailability.
14 The cat’s sense of taste follows a distinct carnivore pattern: taste buds of the facial nerve are highly responsive to amino acids and the sweet receptors are non functioning.

...why these very unique adaptations?

Well, throughout their evolution, cats increasingly specialised as hunters 3. In order to hunt efficiently and run lightning fast, their bodies had to shed any and all excess weight – even from their internal organs.

These deletions enable them to go after their main source of fuel – prey animals. They collectively assisted in cats developing into light framed hunting machines. Very cool.

...the feeding solution to these unique dietary requirements

To meet each and every one of the dietary requirements brought about by their distinct adaptations, house cats need to eat what their ancestors ate – fresh, unprocessed meat.

...this list of adaptations concludes the discussion of Ancestry

Four blog posts collectively discussed the domestic cat’s unique characteristics as obligate, hyper or strict carnivores. It discussed their classification, genetic heritage, anatomy, behaviour and the various adaptations to hyper carnivorism.

...what's next?

The Next post Why do Cats Love Commercial Foods so Much? considers the suitability of commercial cat foods to a cat’s biology. What should House Cats Eat? And why? might interest you as it looks at what house cats should ideally be eating for good health and longevity.

Finally, Can Cats Eat a Vegan Diet? is a two-part discussion that examines how suitable a vegetarian diet is for the domestic cat. It also looks at the ethical considerations of this dietary ideology.

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References

1 Morris, J.G. (2002). Idiosyncratic nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Nutrition Research Reviews, 15, 153 – 168.

2 Bradshaw, J.W.S., Goodwin, D., Legrand-Defrétin, V. & Nott, H.M.R. (1996). Food selection by the domestic cat, an obligate carnivore. Comparative Biochemistry and Physiology Part A: Physiology 114(3), 205 – 209.

3 Animal Wellness Summit (2019, March 20). Live conference on epigenetics with Barney Kuntze and Madeleine Innocent [Video]. Youtube. https://www.youtube.com/watch?v=zsCXf6OPqL4

Information for the 14 facts cards summarised from:

Morris, J.G. (2002). Idiosyncratic nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Nutrition Research Reviews, 15, 153 – 168.

Morris, J.G. (2001). Unique nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Recent Advances in Animal Nutrition in Australia, 13, 187 – 194.

Plantinga, E.A., Bosch, G. & Hendriks, W.H. (2011). Estimation of the dietary nutrient profile of free-roaming feral cats: Possible implications for nutrition of domestic cats. British Journal of Nutrition 106, S35 – S48.

Raw Feeding for IBD Cats (n.d.). Feline nutrition in inflammatory bowel disease. Retrieved November 18, 2021, from https://www.rawfeedingforibdcats.org/feline-nutrition-in-ibd.html

Li, X., Li, W., Wang, H., Bayley, D.L., Cao, J., Reed, D.R., Bachmanov, A.A., Huang, L., Legrand-Defretin, V., Beauchamp, G. K. & Brand, J.G. (2006). Cats lack a sweet taste receptor. The Journal of Nutrition, 136(7), 1932S; https://doi.org/10.1093/jn/136.7.1932S

Bradshaw, J.W.S., Goodwin, D., Legrand-Defrétin, V. & Nott, H.M.R. (1996). Food selection by the domestic cat, an obligate carnivore. Comparative Biochemistry and Physiology Part A: Physiology 114(3), 205 – 209.

Dickinson, P.J., Anderson, P.J.B., Williams, D.C., Powell, H.C., Shelton, G.D., Morris, J.G. & LeCouteur, R.A. (2004). Assessment of the neurologic effects of dietary deficiencies of phenylalanine and tyrosine in cats. Medical Journal of Veterinary Science, 65(5), 671 – 80.

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